Restylane Refyne contains the active ingredient cross linked, non- animal based Butanediol Diglycidyl Ether (BDDE). Optimal Balance Technology allows these dermal fillers to integrate smoothly into the skin, giving a higher acceptance rate by the patient’s skin. OBT ensures an optimal balance between the level of cross-linking and gel calibration that exists due to an equilibrium concentration of hyaluronic acid Individual’s self esteem and confidence are increased as a result of lines and wrinkles instantly being smoothed away. Injected into the mid-deep layer of the skin dermis, Restylane Refyne can be used to reduce the following: Moderate wrinkles and lines, Nasolabial folds, Marionette lines. Results are safe and instant from the first treatment. The overall effects will last from 6 to 9 months and even up to one year depending on the individual’s skin type factors, such as age, lifestyle and technique used.